General Info
| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human/Rhesus |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Mouse monoclonal antibody anti-CD16 is suitable for use in Flow Cytometry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | 3G8 |
| Conjugation: | PE |
| Isotype: | IgG1k |
| Formulation: | PBS with 4mg/ml BSA and 0.1% sodium azide |
| Storage Instruction: | Store at 2-8°C upon receipt. |
Information
| Immunogen: | Human CD16 |
Description
| Background | CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms-a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III) , and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance