General Info
Host: | Rabbit |
Applications: | WB/IF/IP |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-PEBP1 (1-187) is suitable for use in Western Blot, Immunofluorescence and Immunoprecipitation research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 IF/ICC 1:50-1:200 IP 1:20-1:50 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | PEBP1 |
Gene ID: | 5037 |
Uniprot ID: | PEBP1_HUMAN |
Immunogen Region: | 1-187 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human PEBP1 (NP_002558.1). |
Immunogen Sequence: | MPVDLSKWSGPLSLQEVDEQ PQHPLHVTYAGAAVDELGKV LTPTQVKNRPTSISWDGLDS GKLYTLVLTDPDAPSRKDPK YREWHHFLVVNMKGNDISSG TVLSDYVGSGPPKGTGLHRY VWLVYEQDRPLKCDEPILSN RSGDHRGKFKVASFRKKYEL RAPVAGTCYQAEWDDYVPKL YEQLSGK |
Description
Function | Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor. |
Protein Name | Phosphatidylethanolamine-Binding Protein 1 Pebp-1 Hcnppp Neuropolypeptide H3 Prostatic-Binding Protein Raf Kinase Inhibitor Protein Rkip Cleaved Into - Hippocampal Cholinergic Neurostimulating Peptide Hcnp |
Database Links | Reactome: R-HSA-5674135 Reactome: R-HSA-5675221 Reactome: R-HSA-6802946 Reactome: R-HSA-6802948 Reactome: R-HSA-6802952 Reactome: R-HSA-6802955 Reactome: R-HSA-9649948 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Phosphatidylethanolamine-Binding Protein 1 antibody Anti-Pebp-1 antibody Anti-Hcnppp antibody Anti-Neuropolypeptide H3 antibody Anti-Prostatic-Binding Protein antibody Anti-Raf Kinase Inhibitor Protein antibody Anti-Rkip Cleaved Into - Hippocampal Cholinergic Neurostimulating Peptide antibody Anti-Hcnp antibody Anti-PEBP1 antibody Anti-PBP antibody Anti-PEBP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance