General Info
| Host: | Rabbit |
| Applications: | ELISA/IP/WB |
| Reactivity: | Human/Monkey/Mouse/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-SOX2 (50-100) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Purification: | Affinity Purified |
| Concentration: | 0.55-0.75 µg/µl |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150IHC: 1:50-1:150 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
| Immunogen Region: | 50-100 |
| Immunogen: | Synthetic peptide taken within amino acid region 50-100 on human Sex determing region Y-box 2 protein. |
Description
| Background | Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance