Anti-AQP3 antibody (200-250) {Biotin}

Clonality:	Polyclonal
Conjugation:	Biotin
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.50-0.57 µg/µl
Dilution Range:	WB: 1:500 ELISA: 1:10, 000 IP: 1:200 IHC: 1:100 ICC: 1:100 IF: 1:100
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Aqp3
Gene ID:	65133
Uniprot ID:	AQP3_RAT
Immunogen Region:	200-250
Immunogen:	Synthetic peptide taken within amino acid region 200-250 on rat Aquaporin 3 protein.

Tissue Specificity	Detected in kidney medulla and papilla, in collecting duct cells. Detected in colon.
Function	Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
Protein Name	Aquaporin-3 Aqp-3 31.4 Kda Water Channel Protein Aquaglyceroporin-3
Database Links	Reactome: R-RNO-432040 Reactome: -RNO-432047
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Basolateral Cell Membrane
Alternative Antibody Names	Anti-Aquaporin-3 antibody Anti-Aqp-3 antibody Anti-31.4 Kda Water Channel Protein antibody Anti-Aquaglyceroporin-3 antibody Anti-Aqp3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance