General Info
Host: | Mouse |
Applications: | FC |
Reactivity: | Human |
Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 is suitable for use in Flow Cytometry research applications. |
Clonality: | Monoclonal |
Clone ID: | HIT2 |
Conjugation: | APC |
Isotype: | IgG1k |
Formulation: | PBS with 0.05% Proclin300, 1% BSA |
Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Information
Gene Symbol: | CD38 |
Gene ID: | 952 |
Uniprot ID: | CD38_HUMAN |
Description
Tissue Specificity | Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. |
Function | Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion. Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+). Has cADPR hydrolase activity. |
Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 2'-Phospho-Adp-Ribosyl Cyclase 2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase 2'-Phospho-Cyclic-Adp-Ribose Transferase Adp-Ribosyl Cyclase 1 Adprc 1 Cyclic Adp-Ribose Hydrolase 1 Cadpr Hydrolase 1 T10 Cd Antigen Cd38 |
Database Links | Reactome: R-HSA-196807 |
Cellular Localisation | Cell Surface Membrane Single-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 antibody Anti-2'-Phospho-Adp-Ribosyl Cyclase antibody Anti-2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase antibody Anti-2'-Phospho-Cyclic-Adp-Ribose Transferase antibody Anti-Adp-Ribosyl Cyclase 1 antibody Anti-Adprc 1 antibody Anti-Cyclic Adp-Ribose Hydrolase 1 antibody Anti-Cadpr Hydrolase 1 antibody Anti-T10 antibody Anti-Cd Antigen Cd38 antibody Anti-CD38 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance