Anti-ZMPSTE24 antibody (450-480) {FITC}

Clonality:	Polyclonal
Conjugation:	FITC
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.55 µg/µl
Dilution Range:	WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Zmpste24
Gene ID:	230709
Uniprot ID:	FACE1_MOUSE
Immunogen Region:	450-480
Immunogen:	Synthetic peptide taken within amino acid region 450-480 on mouse ZMPSTE24 protein.

Function	Transmembrane metalloprotease whose catalytic activity is critical for processing lamin A/LMNA on the inner nuclear membrane and clearing clogged translocons on the endoplasmic reticulum. Proteolytically removes the C-terminal three residues of farnesylated proteins. Plays also an antiviral role independently of its protease activity by restricting enveloped RNA and DNA viruses. Mechanistically, controls IFITM antiviral pathway to hinder viruses from breaching the endosomal barrier by modulating membrane fluidity.
Protein Name	Caax Prenyl Protease 1 Homolog Farnesylated Proteins-Converting Enzyme 1 Face-1 Prenyl Protein-Specific Endoprotease 1 Zinc Metalloproteinase Ste24 Homolog
Cellular Localisation	Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Nucleus Inner Membrane Early Endosome Membrane Late Endosome Membrane
Alternative Antibody Names	Anti-Caax Prenyl Protease 1 Homolog antibody Anti-Farnesylated Proteins-Converting Enzyme 1 antibody Anti-Face-1 antibody Anti-Prenyl Protein-Specific Endoprotease 1 antibody Anti-Zinc Metalloproteinase Ste24 Homolog antibody Anti-Zmpste24 antibody Anti-Face1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance