TSLP, Human, Standard ABTS ELISA Development Kit

Referencia NB-50-1286-1000

embalaje : 1000Tests

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Product Specifications

Analytical sensitivity

Lot-specific

Assay range

Lot-specific

Hands-on time

1 hr 45 min

Time-to-result

24 hr 30 min

Homogenous (no wash)

No

Instrument

Colorimetric Microplate Reader

Product size

10 x 96 Tests

Contents

This Human TSLP ELISA Kit includes Capture Antibody, Detection Antibody, Protein Standard, and HRP-conjugate. The HRP-conjugate is packaged separately.

Storage

Refer to product documentation for component specific storage temperature.

Protein name

TSLP

Protein family

Growth Factors & Receptors

Species (tested)

Human

Assay kit format

ELISA Development Kit

Detector antibody conjugate

Biotin

Label or dye

HRP

About This Kit

900-K334K consists of: 900-K334 (capture antibody, detection antibody, and protein standard), and AVIDIN-60UL (avidin HRP-conjugate).

Human TSLP ABTS ELISA Development Kit contains the key components required for the quantitative measurement of natural and/or recombinant human TSLP in a sandwich ELISA format. Human TSLP ABTS ELISA Development Kit contains enough material to assay the target cytokine in at least 1,000 ELISA plate wells.

The ABTS ELISA Buffer Kit (Product # 900-K00), sold separately, is recommended to be used in conjunction with this ABTS ELISA Development Kit for optimal performance. This buffer kit contains all the necessary components to assay ten 96-well ELISA plates (included) and contains detailed handling instructions.

Target information

TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c (+) dendritic cells, naive CD4 (+), and CD8 (+) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation. TSLP influences the regulation of the positive selection of regulatory T cells and maintenance of peripheral CD4 (+) T cell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis. It is expressed in heart, liver and prostate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.