General Info
| Host: | Rabbit |
| Applications: | WB/IF/IP |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-PEBP1 (1-187) is suitable for use in Western Blot, Immunofluorescence and Immunoprecipitation research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:1000IF/ICC 1:50-1:200IP 1:20-1:50 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | PEBP1 |
| Gene ID: | 5037 |
| Uniprot ID: | PEBP1_HUMAN |
| Immunogen Region: | 1-187 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human PEBP1 (NP_002558.1). |
| Immunogen Sequence: | MPVDLSKWSGPLSLQEVDEQ PQHPLHVTYAGAAVDELGKV LTPTQVKNRPTSISWDGLDS GKLYTLVLTDPDAPSRKDPK YREWHHFLVVNMKGNDISSG TVLSDYVGSGPPKGTGLHRY VWLVYEQDRPLKCDEPILSN RSGDHRGKFKVASFRKKYEL RAPVAGTCYQAEWDDYVPKL YEQLSGK |
Description
| Function | Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor. |
| Protein Name | Phosphatidylethanolamine-Binding Protein 1Pebp-1HcnpppNeuropolypeptide H3Prostatic-Binding ProteinRaf Kinase Inhibitor ProteinRkip Cleaved Into - Hippocampal Cholinergic Neurostimulating PeptideHcnp |
| Database Links | Reactome: R-HSA-5674135Reactome: R-HSA-5675221Reactome: R-HSA-6802946Reactome: R-HSA-6802948Reactome: R-HSA-6802952Reactome: R-HSA-6802955Reactome: R-HSA-9649948 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Phosphatidylethanolamine-Binding Protein 1 antibodyAnti-Pebp-1 antibodyAnti-Hcnppp antibodyAnti-Neuropolypeptide H3 antibodyAnti-Prostatic-Binding Protein antibodyAnti-Raf Kinase Inhibitor Protein antibodyAnti-Rkip Cleaved Into - Hippocampal Cholinergic Neurostimulating Peptide antibodyAnti-Hcnp antibodyAnti-PEBP1 antibodyAnti-PBP antibodyAnti-PEBP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance