Anti-SOX10 antibody (400-450) {FITC}

Clonality:	Polyclonal
Conjugation:	FITC
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.55-0.75 µg/µl
Dilution Range:	WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:150 IHC: 1:50-1:100
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	SOX10
Gene ID:	6663
Uniprot ID:	SOX10_HUMAN
Immunogen Region:	400-450
Immunogen:	Synthetic peptide taken within amino acid region 400-450 on human Transcription Factor SOX-10 protein.

Tissue Specificity	Expressed in fetal brain and in adult brain, heart, small intestine and colon.
Function	Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3. Transcriptional activator of MBP, via binding to the gene promoter.
Protein Name	Transcription Factor Sox-10
Database Links	Reactome: R-HSA-9619665 Reactome: R-HSA-9764302
Cellular Localisation	Cytoplasm Nucleus Mitochondrion Outer Membrane Peripheral Membrane Protein Cytoplasmic Side
Alternative Antibody Names	Anti-Transcription Factor Sox-10 antibody Anti-SOX10 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance