Glycodeoxycholate Sodium [16409-34-0]

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Référence NB-64-29681-100mg

Conditionnement : 100mg

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Glycodeoxycholate Sodium

Alias Sodium glycyldeoxycholate, Sodium glycodeoxycholate, Glycodeoxycholic acid sodium salt

The mechanism by which Glycodeoxycholate Sodium induces apoptosis in hepatocytes is related to DNA cleavage by endonucleases. It is a secondary bile acid produced by the action of enzymes present in the microflora of the colonic environment.

Glycodeoxycholate Sodium
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Purity:99.57%
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Product Introduction

Bioactivity
Description
The mechanism by which Glycodeoxycholate Sodium induces apoptosis in hepatocytes is related to DNA cleavage by endonucleases. It is a secondary bile acid produced by the action of enzymes present in the microflora of the colonic environment.
SynonymsSodium glycyldeoxycholate, Sodium glycodeoxycholate, Glycodeoxycholic acid sodium salt
Chemical Properties
Molecular Weight471.61
FormulaC26H42NNaO5
Cas No.16409-34-0
Smiles[Na+].C[C@H](CCC(=O)NCC([O-])=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (106.02 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.24 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1204 mL10.6020 mL21.2040 mL106.0198 mL
5 mM0.4241 mL2.1204 mL4.2408 mL21.2040 mL
10 mM0.2120 mL1.0602 mL2.1204 mL10.6020 mL
20 mM0.1060 mL0.5301 mL1.0602 mL5.3010 mL
50 mM0.0424 mL0.2120 mL0.4241 mL2.1204 mL
100 mM0.0212 mL0.1060 mL0.2120 mL1.0602 mL