General Info
Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse/Rat/Salamander/Pig |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Sarcoplasmic/endoplasmic reticulum calcium ATPase 1-ATPase 1 ATPase (548-597 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:10000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | ATP2A1 |
Gene ID: | 487 |
Uniprot ID: | AT2A1_HUMAN |
Immunogen Region: | 548-597 aa |
Specificity: | SERCA1 Polyclonal Antibody detects endogenous levels of SERCA1 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human ATP2A1 at the amino acid range 548-597 |
Description
Function | Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. |
Protein Name | Sarcoplasmic/Endoplasmic Reticulum Calcium Atpase 1 Serca1 Sr Ca(2+-Atpase 1 Calcium Pump 1 Calcium-Transporting Atpase Sarcoplasmic Reticulum Type - Fast Twitch Skeletal Muscle Isoform Endoplasmic Reticulum Class 1/2 Ca(2+ Atpase |
Database Links | Reactome: R-HSA-1912420 Reactome: R-HSA-418359 Reactome: R-HSA-5578775 Reactome: R-HSA-936837 |
Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Sarcoplasmic Reticulum Membrane |
Alternative Antibody Names | Anti-Sarcoplasmic/Endoplasmic Reticulum Calcium Atpase 1 antibody Anti-Serca1 antibody Anti-Sr Ca(2+-Atpase 1 antibody Anti-Calcium Pump 1 antibody Anti-Calcium-Transporting Atpase Sarcoplasmic Reticulum Type - Fast Twitch Skeletal Muscle Isoform antibody Anti-Endoplasmic Reticulum Class 1/2 Ca(2+ Atpase antibody Anti-ATP2A1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance