SARS-CoV-2 - Clevudine - Therapeutic Candidates

SARS-CoV-2 - Clevudine - Therapeutic Candidates

 

Clevudine, marketed as Levovir and Revovir, is a synthetic pyrimidine analogue. It is an antiviral drug used in the treatment of hepatitis B. In cells, clevudine is phosphorylated into its active metabolites, clevudine monophosphate and clevudine triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, causing DNA chain termination and inhibiting the function of the hepatitis B virus (HBV) DNA polymerase (reverse transcriptase). Clevudine has a long half-life and exhibits a significant reduction in covalently closed circular DNA (cDNA), so that the patient is less likely to relapse after cessation of treatment.
A study is currently underway to evaluate the safety and efficacy of clevudine in patients with a moderate form of COVID-19 caused by CoV-2 SARS. In this Phase 2 study, clevudine is combined with hydroxychloroquine.

 

 

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Description
Cond.
Price Bef. VAT
NB-64-35002-5mg
 5mg 
NB-64-35002-25mg
 25mg 
NB-64-35002-100mg
 100mg 
NB-64-35002-10mg
 10mg 
NB-64-35002-50mg
 50mg 
NB-64-35002-1mL
 1mL 
NB-64-35004-25mg
 25mg 
NB-64-35004-100mg
 100mg 
NB-64-35004-50mg
 50mg 
NB-64-34295-25mg
 25mg 
NB-64-34295-50mg
 50mg 
NB-64-34295-100mg
 100mg