General Info
Host: | Rabbit |
Applications: | ELISA/WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-MIEN1 (1-50) is suitable for use in ELISA and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | FITC |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.65-0.83 µg/µl |
Dilution Range: | WB: 1:500-1:1, 000DB: 1:2, 000ELISA: 1:2, 000 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
Gene Symbol: | MIEN1 |
Gene ID: | 84299 |
Uniprot ID: | MIEN1_HUMAN |
Immunogen Region: | 1-50 |
Immunogen: | Synthetic peptide taken within amino acid region 1-50 on human XTP4 protein. |
Description
Tissue Specificity | Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level). |
Post Translational Modifications | Isoprenylation facilitates association with the plasma membrane and enhances the migratory phenotype of cells by inducing increased filopodia formation. |
Function | Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process. |
Protein Name | Migration And Invasion Enhancer 1Hbv X-Transactivated Gene 4 ProteinHbv Xag-Transactivated Protein 4Protein C35 |
Cellular Localisation | CytoplasmCytosolCell MembraneLipid-AnchorCytoplasmic SideConcentrates At The Leading Edge Of Migrating CellsLocalizes Outside Membrane Raft Regions |
Alternative Antibody Names | Anti-Migration And Invasion Enhancer 1 antibodyAnti-Hbv X-Transactivated Gene 4 Protein antibodyAnti-Hbv Xag-Transactivated Protein 4 antibodyAnti-Protein C35 antibodyAnti-MIEN1 antibodyAnti-C17orf37 antibodyAnti-RDX12 antibodyAnti-XTP4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance