General Info
Host: | Rabbit |
Applications: | ELISA/ICC/IF/IHC/IP/WB |
Reactivity: | Bovine/Human/Mouse/Rat/Sheep |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-AQP1 (215-265) is suitable for use in ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | FITC |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.55-0.59 µg/µl |
Dilution Range: | WB: 1:500 ELISA: 1:10, 000 IP: 1:200 IHC: 1:100 ICC: 1:100 IF: 1:100 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
Gene Symbol: | AQP1 |
Gene ID: | 358 |
Uniprot ID: | AQP1_HUMAN |
Immunogen Region: | 215-265 |
Immunogen: | Synthetic peptide taken within amino acid region 215-265 on human Aquaporin 1 protein. |
Description
Tissue Specificity | Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver. |
Function | Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane. |
Protein Name | Aquaporin-1 Aqp-1 Aquaporin-Chip Urine Water Channel Water Channel Protein For Red Blood Cells And Kidney Proximal Tubule |
Database Links | Reactome: R-HSA-1237044 Reactome: R-HSA-1247673 Reactome: R-HSA-432040 Reactome: R-HSA-432047 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Aquaporin-1 antibody Anti-Aqp-1 antibody Anti-Aquaporin-Chip antibody Anti-Urine Water Channel antibody Anti-Water Channel Protein For Red Blood Cells And Kidney Proximal Tubule antibody Anti-AQP1 antibody Anti-CHIP28 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance