General Info
| Host: | Armenian Hamster |
| Applications: | FC |
| Reactivity: | Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: | Armenian Hamster monoclonal antibody anti-C-X-C chemokine receptor type 3 is suitable for use in Flow Cytometry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | CXCR3-173 |
| Conjugation: | AF647 |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 1% BSA |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Information
| Gene Symbol: | Cxcr3 |
| Gene ID: | 12766 |
| Uniprot ID: | CXCR3_MOUSE |
Description
| Tissue Specificity | Expresses in lymphoid organs and Th1 cells. |
| Post Translational Modifications | Sulfation on Tyr-27 and Tyr-29 is essential for CXCL10 binding. N-glycosylated. |
| Function | Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response. Binds to CCL21. |
| Protein Name | C-X-C Chemokine Receptor Type 3Cxc-R3Cxcr-3Interferon-Inducible Protein 10 ReceptorIp-10 ReceptorCd Antigen Cd183 |
| Database Links | Reactome: R-MMU-380108Reactome: -MMU-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-X-C Chemokine Receptor Type 3 antibodyAnti-Cxc-R3 antibodyAnti-Cxcr-3 antibodyAnti-Interferon-Inducible Protein 10 Receptor antibodyAnti-Ip-10 Receptor antibodyAnti-Cd Antigen Cd183 antibodyAnti-Cxcr3 antibodyAnti-Cmkar3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance