General Info
| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Mouse monoclonal antibody anti-CD226 is suitable for use in Flow Cytometry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | DX11 |
| Conjugation: | FITC |
| Isotype: | IgG1 |
| Formulation: | PBS with 0.09% sodium azide and 1% BSA |
| Concentration: | 0.1 mg/mL |
| Storage Instruction: | Store at 2-8°C upon receipt. |
Information
| Gene Symbol: | CD226 |
| Gene ID: | 10666 |
| Uniprot ID: | CD226_HUMAN |
| Immunogen: | Human cytotoxic T lymphocyte clone |
Description
| Tissue Specificity | Expressed by peripheral blood T-lymphocytes. |
| Function | Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding. |
| Protein Name | Cd226 AntigenDnax Accessory Molecule 1Dnam-1Cd Antigen Cd226 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cd226 Antigen antibodyAnti-Dnax Accessory Molecule 1 antibodyAnti-Dnam-1 antibodyAnti-Cd Antigen Cd226 antibodyAnti-CD226 antibodyAnti-DNAM1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance